Module 7 : Microbial Molecular Biology and Genetics

Lecture 6 : DNA Repair and Microbial Recombination

 

Study Questions:

  1. 1. Define: DNA repair
  2. 2. What is photo-reactivation?

    3. Which enzyme is responsible for photo-reactivation?

    4. What do you mean by Aberrant methylation and the enzyme responsible for this action?

    5. What are the general features of excision type repair pathways?

    6. Enzymes required for Base excision repair and their role in BER?

    7. What is Nucleotide-Excision repair (NER)?

    8. What is the difference between BER and NER?

    9. Replicative errors are rectified by……………………..?

    10. What is DNA base Mismatch repair? How does it occur in cell?

    11. What is DNA recombination?

    12. What do you mean by homologous recombination and non homologous recombination?

    13. What is the difference between homologous and non homologous recombination?

    14. What is site specific recombination?

    15. What is replicative recombination?

    16. What are the different types of homologous recombination?

    17. What is Holiday model?

    18. Explain in detail about Holiday model?

    19. What do you mean by branch migration?

    20. What is known as Holiday Junction?

    21. What is Szoztak model (Double strand break repair model)?

    22. Explain: Non-homologous end joining method

    23. Explain: Site specific recombination and the enzymes involved in this process