Study Questions:

1. 1. Which strain had a killing property?

   2. What do you infer from the Griffith experiments?

   3. What may be the reason for dying of mice when heat killed S-strain mixed with Live R-strain?

2. 4. What is the finding of Avery-MacLeod-McCarty Experiment and how they did to conclude the experiment?

5. 5. What is Harshey – Chase experiments and how they have done it?

   6. Why did they choose radioactive phosphorous and sulfur?

   7. What are Nucleotide and its components?

   8. What is purine and pyrimidine and explain its bonding pattern between them?

   9. Draw any one structure of nucleotide with all three components with correct bonding pattern?

   10. Name of the bond which connects the base and sugar residue?

   11. Are there any differences between DNA and RNA? If so, explain in detail?

   12. What is Charaff's rule?

   13. What is DNA? And who discovered the DNA Molecule in which year?

   14. How many Nucleotides are there in single pitch and its length? What is major and minor grooves and their role?

   15. What is the radius of the double helical DNA?

   16. What is the name of the sugar molecule present in the DNA? Is it six carbon or five carbon? How will you call it?

   17. What is the name of the bond which connects two nucleotides together? And draw the structure of how they are bonding?

   18. Directionality of the double stranded DNA? What is the name of the molecule from which it starting and also the molecule present at the end?

   19. What is complementary base pairing? Can you write the interactions happen in complementary base pairing?

   20. Different ways to produce single stranded DNA molecule from Double stranded DNA?

   21. What are the different types of DNA molecule, and why they are different?

   22. What is RNA? Name the bases that RNA contains?

   23. What are all the modified bases of mature RNA?

   24. What is the importance in the presence of 2' Hydroxyl group on RNA?

   25. Name some secondary structures of the RNA?