Mechanism

The reactions involve the oxidative addition followed by reductive elimination via transmetllation and cis-trans isomerization (Scheme 9).

In case of alkyl halide, an influence of 1,3-butadiene on the reaction has been noted (Scheme 10).

Scheme 10

Mechanism

The acceleration of the reaction with butadiene is described in Scheme 11.

Scheme 11

Examples:

J. Terao, H. Watanabe, A. Ikumi, H. Kuniysu, N. Kambe , J. Am. Chem. Soc. 2002 , 124 , 4222.

G. Y. Li, W. J. Marshall, Organometallics 2002 , 21 , 590.

 

11.9.3.3 Suzuki Coupling

Nickel complexes having nitrogen based ligands catalyze the Suzuki coupling with secondary halides (Scheme 12).

Scheme 12