Examples:
1.2.2.2 The Thorpe-Ziegler Reaction
The cyclization of dinitriles using base can be accomplished (Scheme 3). Although it is similar to the Dieckmann reaction, the former is often better compared to the latter.
Scheme 3
Examples:
Module 1: Formation of Aliphatic Carbon-Carbon Bonds: Base Catalyzed Reactions
Lecture 2 : Base Catalyzed Reactions - II
Examples:
1.2.2.2 The Thorpe-Ziegler Reaction
The cyclization of dinitriles using base can be accomplished (Scheme 3). Although it is similar to the Dieckmann reaction, the former is often better compared to the latter.
Scheme 3
Examples: