Module 4 : Molecular Cell Biology

Lecture 28 : Transcription (Part-I)

 

Figure 28.8 : Stem hairpin loop structure

Steps in intrinsic termination: Different steps which are involved in intrinsic termination are described here in figure 1.9. These steps are as follows:  
1) Here, two inverted repeats GCCCGC are present in the DNA template which is transcribed

2) Nearly 6 adenines residues follow the second inverted repeat GCCCGC, given below in Figure 28.9(a).

Figure 28.9(a) : Inverted repeat are following  by adenine residues

Now inverted repeats are forming a hairpin structure which pause the polymerase

Figure 28.9(b) : Formation of  Stem loop structure