4.3.1.8 Doebner Reaction (Beyer Synthesis)
Aryl amine reacts with aldehydes and enolizable carbonyl compounds via condensation followed by aromatic electrophilic substitution and autoxidation to give quinolines.
Mechanism
Examples:
Module 4: Formation of Aliphatic Carbon-Nitrogen Bonds
Lecture 11 : Carbon-Nitrogen Bonds Formation - II
4.3.1.8 Doebner Reaction (Beyer Synthesis)
Aryl amine reacts with aldehydes and enolizable carbonyl compounds via condensation followed by aromatic electrophilic substitution and autoxidation to give quinolines.
Mechanism
Examples: