4.3.1.5 Gabriel-Cromwell Reaction
Amines react with α -bromoacrylates to give aziridines in the presence of base.
Mechanism
Examples:
Module 4: Formation of Aliphatic Carbon-Nitrogen Bonds
Lecture 11 : Carbon-Nitrogen Bonds Formation - II
4.3.1.5 Gabriel-Cromwell Reaction
Amines react with α -bromoacrylates to give aziridines in the presence of base.
Mechanism
Examples: