Module 4 : Bioorganic Chemistry of Nucleic Acids

Lecture 2 : Hydrogen Bonded Base Pairs and Double Helix

4.10.4.7. B-type Duplex is not Possible for RNA

Although B-DNA solved by Watson and Crick is the major form of DNA in chromosomes, other types of secondary structure are possible. For example, duplexes containing RNA cannot form B type duplex because of the steric clash between its 2'-OH and the phosphodiester. Instead, it forms an A-type duplex.

4.10.4.8. SOME OTHER TYPE OF BASE PAIRING AND DNA SECONDARY STRCTURE

4.10.4.9. WOBBLE BASE PAIRS AND RNA SECONDARY STRUCTURE