Module 3 : Organometallic Reagents

Lecture 6 : Organolithium Reagents

   

Examples:


3.3.7.5 Parham Cyclization

The halogen-metal exchange on an aromatic ring followed by a ring-closure reaction with the electrophiles as part of the side chain occupies a place of choice for the assembling of carbo and heterocyclic systems (Scheme 21).

Scheme 21

Examples: