Regulation of Glycolysis-

1. Uptake of glucose from blood- The level of glucose present in a cell determines the availability of sugar for oxidation via glycolysis. Glucose transport in cell is regulated by several cell surface receptor which are under the control of insulin (Figure 5.2). Insulin upregulates the level of glucose transporters Glut-3 or Glut-4 and increases the uptake of glucose from blood stream. In addition, insulin also regulates breakdown of glycogen to increase the amount of available glucose.

Figure 5.2: Regulation of uptake of glucose in the cell through action of insulin and cell surface receptors.