Module 6 : Bioinformatics tools

Lecture 40 : Computer Aided Drug Design

HOME ASSIGNMENT

1. Go to the plasmodium falciparum genome database (www.plasmodb.org) and down load the protein sequence with the plasmodb ID PFD0975w.

2. Identify the suitable template and perform homology modeling to prepare the 3-D model of the PFD0975w.

3. Search similar molecules to the ATP molecule from the Zinc Database (http://zinc.docking.org/). Download the molecules.

4. Perform docking of these molecules on the 3-D model of PFD0975w with the help of Autodock 4.1.