Fig7-3.2.1: Map of the recombinant plasmid vector containing cDNA sequence for insulin polypeptide (Chain A or B)

7-3.3 Production of Growth Hormones:

Growth hormone is one of the most important hormones in human body. The core center for production of growth hormone is pituitary gland. The action of growth hormone is either direct or indirect on the human physiological process. But in some children, malfunction of growth hormone results in abnormal growth of the individual. In case of these conditions recombinant growth hormone is useful for the treatment.

Human growth hormone has versatile functions:

• Activates the production of protein in cells by releasing some essential factors.
  
  
• Helps in fastening the production of DNA and RNA.
  
  
• Accelerates the generation of red blood cells and augments the flow of blood to the kidneys and the rate at which the kidney does its vital filtration work.
  
  
• Plays a major role in maintaining the level of fats in the body
  
  
• Activates bone growth and skeletal development indirectly by producing intermediate factor IGF-1.