Module 1 : INTRODUCTION

Lecture 1 : Role of Genes within Cells, Genetic Code etc.


Fig 1-1.2: Organization of genes in DNA of a chromosome

1-1.3 Genome:

Genome is the complete set of genetic information of a cell or an organism; in particular, the complete sequence of DNA/RNA that carries this information. In diploid organisms, it refers to the haploid set of chromosomes present in a cell. Depending on its localization, genome may be nuclear or organellar. Organellar genomes are again of two types: mitochondrial and chloroplast genome. Genome size of organisms differs significantly between different species. The size of the genome governs the size and complexity of an organism. However, many small sized organisms, in fact have bigger genomes than their larger counterparts.

Various organisms have different sized genome as can be seen in the table below.

Species

Organism

Genome Size (Mb)

Triticum aestivum

Plant

16000

Homo sapiens

Mammal

3200

Arabidopsis thaliana

Plant

125

Drosophila melanogaster

Insect

180

Caenorhabditis elegans

Nematode worm

97

Saccharomyces cerevisiae

Yeast

12.1

Escherichia coli

Bacterium

4.64

Haemophilus influenzae

Bacterium

1.83

Mycoplasma genitalium

Bacterium

0.58