Module 4 : Molecular Cell Biology

Lecture 21 : Prokaryotic Cell

 

1. Outer Flagella: A flagellum attached to the bacterial capsule is a central feature of most of the prokaryotic cell especially motile bacteria. It provides motion or locomotion to the bacteria and be responsible for chemotaxsis of bacteria. Movement of bacteria towards a chemical gradient (such as glucose) is known as chemotaxsis. Flagellum is a part of cell wall and its motion is regulated by motor protein present inside the cell. Flagellar motion is an energy consuming process and governed by ATPase present at the bottom of the shaft. It is made up of protein flagellin and reduction or suppression of flagellar protein reduces bacterial infectivity (pathogenicity) and ability to grow.

Figure 21.1: Structural details of a typical prokaryotic cell. (A) Whole cell and (B) composition of cell wall of gram negative and positive bacteria.

2. Bacterial surface layers: Bacteria posses 3 anatomical barriers to protect the cells from external damage. Bacterial capsule is the outer most layer and made up of high molecular weight polysaccharides. It is impermeable to the water or other aqueous solvent and it is responsible for antigenicity of bacterial cells. Cell wall in bacteria and its response to gram staining is the basis of classification of bacterial species.