Polymer supported Ti(IV) catalyst was explored for some carbon-carbon bond forming reactions including allylation, cyanation and ene reactions (Scheme 6).⁹

Scheme 6

Seebach and co-workers have developed polymer supported Ti-TADDOLate for enantioselective diethyl zinc addition to aldehydes.¹⁰ It showed high activity as well as enantioselectivity (Scheme 7).

Scheme 7

Chiral amino alcohol immobilized polyethylene (PE) fibers has been synthesized by electron beam induced perirradiation graft copolymerization method (Scheme 8).¹¹ This more stable fibrous catalyst was used in phenylacetylene addition to benzaldehyde with Zn(OTf)₂.

Scheme 8

Cross-linked polymer supported Ti(O_iPr)₂.BINOLate complex was reported for enantioselective diethyl zinc and trimethylsilyl cyanide addition reaction with aldehydes (Scheme 9).¹²

Scheme 9