1.9.6 N-Methylmorpholine-N-oxide (NMO)
NMO is a useful and relatively mild oxidizing agent. It is used as a co-oxidant with OSO4 for hydroxylation of alkenes (Scheme 1). In the presence of oxidizing agent such MCPBA catalytic amount of NMO can be used.
M. R. Sivik, Encyclopedia of Reagents for Organic Synthesis, John Wiley and Sons, Inc., L. A. Paquette, Ed., New York, 1995, 5, 3545. |
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Scheme 1 |
Examples:
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Scheme 2 |
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Scheme 3 |