Module 2 : ENZYMES IN GENETIC ENGINEERING

Lecture 3 : Enzymes in Modification- Phosphatases and Methylases and their Mechanism of Action


Bibliography:

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•  Gerstein A.S. 2004. Molecular Biology Problem Solver: A Laboratory Guide . John Wiley & Sons.

•  Henthorn P.S., Raducha M., Edwards Y.H., Weiss M.J., Slaughter C., Lafferty M.A., Harris H. 1987. Nucleotide and amino acid sequences of human intestinal alkaline phosphatase: close homology to placental alkaline phosphatase. PNAS . 84 : 1234-1238.

•  Kim E. E., Wyckoff H. W. 1991. Reaction mechanism of alkaline phosphatase based on crystal structures to metal-ion catalysis. J. Mol. Biol . 218:449-464.

•  Knoll B., Rothblum K., Longley M. 1988. Nucleotide sequence of the human placental alkaline phosphatase gene: Evolution of the 5' flanking region by deletion/substitution. J. Biol. Chem. 263: 12020-12027.

•  Millan, J. L. and Manes, T. 1988. Seminoma-derived Nagao isozyme is encoded by a germ-cell alkaline phosphatase gene. PNAS . 85 : 3024-3028.