Organic chemistry of non-metal phosphorus, metalloids such as arsine and antimony along with metallic element bismuth is termed as organoelement chemistry.

The importance given to organoarsenic compounds earlier due to their medicinal values was waded out after antibiotics were discovered and also their carcinogenic and toxic properties were revealed. Also, the synthetically important organometallic compounds of group 13 and 14 masked the growth of group 15 elements. However, the organoelement compounds of phosphorus, arsenic and antimony find usefulness as ligands in transition metal chemistry due to their σ-donor and π-acceptor abilities which can be readily tuned by simply changing the substituents. These donor properties are very useful in tuning them as ligands to make suitable metal complexes for metal mediated homogeneous catalysis. Although organoelement compounds can be formed in both +3 (trivalent and tricoordinated) and +5(pentavalent and tetra or pentacoordinated) oxidation states, trivalent compounds are important in coordination chemistry.

For organoelement compounds of group 15, the energy of E—C bond decreases in the order, E = P > As > Sb > Bi, and in the same sequence E—C bond polarity increases.