Chapter 13

Oxidation Reactions

 
  • Another similar oxidant is PDC (pyridiniumdichromate) .
Since PDC is less acidic than PCC it is often used to oxidize alcohols that may be sensitive to acids.
In methylene chloride solution, PDC oxidizes primary and secondary alcohols in roughly the same fashion as PCC, but much more slowly.
However, in DMF solution saturated primary alcohols are oxidized to carboxylic acids.
In both solvents allylic alcohols are oxidized efficiently to conjugated enals and enones respectively.