Module 1 : Basics of proteomics
Lecture 1 : Genomics to Proteomics
 
PREAMBLE
   A gene is a stretch of nucleotides that ultimately codes for a polypeptide, which in turn are of structural or functional significance to the cell or the organism. The entire sequence of an organism’s hereditary information, including coding and non-coding regions, encoded in DNA is known as “genome”. Studying genome, including function and interaction of all the genes of an organism is known as genomics. Success of genome sequencing projects has been remarkable; however, in spite of availability of the entire genome being sequenced, the complex biological processes cannot be unraveled until the role of each of the gene expression products is understood.  Proteomics is study of the entire protein complement of an organism, under a given set of conditions. Proteomic studies rely on tools that entail understanding the biochemistry of proteins and the pathways in which these proteins participate in order to bring about a well-orchestrated and harmonious functioning of a given cell or organism in consideration.